THE blood of a white female (Mrs. L. M.) was submitted for testing following the birth of her first infant, who was slightly anæmic at the age of 2–3 weeks. The maternal serum contained anti-e. Her red cells failed to react with 5 anti-D, 5 anti-C, 13 anti-E, 14 anti-c, 9 anti-e, 1 anti-f, 2 anti-CW, 1 anti-CX, 3 anti-Ce(rhi), 1 anti-hrs, and 1 anti-G. The red cells also failed to react with the sera of four immunized –D–/–D– individuals. Her phenotype can be represented as – – –/– – – or as suggested by Ceppellini1 as “Rhnull”. The other antigens—A1, N, s, k, Fy(a + b −), Jk(a −), Le(a − b +)—appeared to be normal.
Ceppellini, R. (personal communication).
Vos, G. H., Vos, Dell, Kirk, R. E., and Sanger, Ruth, Lancet, i, 14 (1961).
Levine, P., Celano, M. J., Vos, G. H., and Morrison, J., Nature, 194, 304 (1962).
Gibbs, M. E., Levine, P., White Chambers, J., Hunter, jun., O. B., and English, C. T., Paper given at the seventeenth annual meeting, Amer. Assoc. Blood Banks, Washington, D.C. (1964).
Levine, P., Celano, M. J., Wallace, J., and Sanger, Ruth, Nature, 198, 596 (1963).
Landsteiner, K., and Wiener, A. S., Proc. Soc. Exp. Biol., 43, 223 (1940).
Levine, P., Hunter, jun., O. B., White Chambers, J., Celano, M. J., English, C. T., and Falkowski, F., Paper given at the seventeenth annual meeting, Amer. Assoc. Blood Banks, Washington, D.C. (1964).
Levine, P., and Celano, M. J., Nature, 193, 184 (1962).
Levine, P., Robinson, E., Celano, M. J., Briggs, O., and Falkinburg, L., J. Hematol., 10, 1100 (1955).
Swanson, J., and Matson, A. G., Transfusion, 4, 257 (1964).
About this article
DNA-minisatellite mutations: Recent investigations concerning distribution and impact on parentage testing
International Journal of Legal Medicine (1993)
Human Genetics (1970)