Letter | Published:

Dipyrrylvinyl Pyridines as Trichuricides

Nature volume 204, page 892 (28 November 1964) | Download Citation



WHIPWORM infections in man and dog have been, until recent years, quite difficult to eradicate. During the past decade several compounds have been found to have activity against these worms. These compounds are ‘Phthalofyne’ orally1 or intravenously2, dithiazanine iodide3, stilbazium iodide4,5, and ‘Glycobiarsol’6. However, most of these drugs require large doses in mg/kg or a series of doses, or they have undesirable side-effects, or the worm loss is not high enough. Among the numerous modifications of stilbazium iodide4 which were prepared, a number of members of the dipyrryl vinyl pyridines were found to have activity against the dog whipworm, Trichuris vulpis.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    , J. Parasit., 40, 481 (1954).

  2. 2.

    , , and , J. Amer. Vet. Med. Assoc., 131, 568 (1957).

  3. 3.

    , , and , Amer. J. Trop. Med. and Hyg., 6, 894 (1957).

  4. 4.

    , and , Nature, 191, 707 (1961).

  5. 5.

    , and , J. Parasit., 48, 769 (1962).

  6. 6.

    , , and , Amer. J. Vet. Res., 24, 819 (1963).

Download references

Author information


  1. Wellcome Research Laboratories, Burroughs Wellcome and Co. (U.S.A.), Inc., Tuckahoe, New York.

    • A. P. PHILLIPS
    •  & R. B. BURROWS


  1. Search for A. P. PHILLIPS in:

  2. Search for R. B. BURROWS in:

About this article

Publication history





By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.