Letter | Published:

Prevention of Cerebral Œdema induced by Triethyltin in Rabbits by Cortico-steroids

Subjects

Abstract

PATIENTS receiving cortico-steroid therapy who underwent craniotomy were observed to have a smoother post-operative course than would have been expected1. Surgeons were thus led deliberately to administer cortico-steroid preparations before and after craniotomy, in order to ease the patient's course. In particular, patients diagnosed as having cerebral œdema, either from a tumour or more diffuse cause, seemed to benefit2, and the improvement is explained on the assumption that this treatment reduces the cerebral œdema. The most recent preparation used has been dexamethasone since it is supposed to have minimal water- and sodium-retaining properties.

References

  1. 1

    Rasmussen, T., and Gulati, D. R., J. Neurosurg., 19, 535 (1962).

  2. 2

    Galicich, J. H., and French, L. A., Amer. Practitioner, 12, 169 (1961).

  3. 3

    Pappius, H. M., and Gulati, D. R., Acta Neuropath., 2, 451 (1963).

  4. 4

    Lippert, R. G., Svien, H. J., Grindlay, J. H., Goldstein, N. P., and Gastineau, C. F., J. Neurosurg., 17, 583 (1960).

  5. 5

    Plum, F., Alvord, E. C., and Posner, J. B., Amer. Med. Assoc. Arch. Neurol., 9, 21 (1964).

  6. 6

    Aleu, F., Katzman, R., and Terry, R. D., J. Neuropath. and Exp. Neurol., 23, 403 (1963).

  7. 7

    Torack, R. M., Terry, R. D., and Zimmerman, H., Amer. J. Path., 36, 273 (1960).

Download references

Author information

Rights and permissions

To obtain permission to re-use content from this article visit RightsLink.

About this article

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.