Letter | Published:

Compensatory Growth of Villi in Postmature Human Placentæ

Nature volume 204, pages 703704 (14 November 1964) | Download Citation



HISTOLOGICAL, changes have been investigated in the postmature human placenta. This is an obstetric abnormality known to be associated frequently with antenatal asphyxia and stillbirth. Fœtal loss occurs as a result of hypoxia, attributed to functional placental insufficiency1–4. It is generally stated that in postmaturity the placenta displays signs of ageing and degeneration: widespread vascular obliteration, thrombosis and infarction with excessive fibrinoid and calcined deposits. The appearance of ‘young’ placental villi in postmaturity, reported by certain investigators5–7, does not seem to have received adequate attention.

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    , Prolonged Gestation (Medgiz, Moscow, 1949).

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    , in Biologie und Pathologie des Weibes, edit. by Seitz, L., and Amreich, A. I., 7 (Urban and Schwarzenberg, München, 1952).

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    , Arch. Gynäk., 188, 12 (1956).

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    , Arch. Gynäk., 191, 297 (1958).

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    , Zbl. Gynäk., 72, 1530 (1950).

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    , in Voprosy Akusherstva i Ginekologii, edit. by Lelchuk, P. Ya., 1, 73, 89 (Rostov-on-the-Don, 1959).

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    , Thesis (Moscow, 1962).

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    , Yezhegodnik Inst. Exp. Med., 7–8, 1, 157 (Leningrad, 1963).

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    , and , Akush. Ginek. (in the press).

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  1. Department of Embryology, Institute of Experimental Medicine, Kirovski prosp. 69/71.

    • Z. P. ZHEMKOVA
  2. Department of Obstetrics and Gynaecology, First Medical Institute, Ul. Lva Tolstogo 6–8, Leningrad-22, U.S.S.R.



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