Abstract
THE effects of repeated dosages of pentobarbital sodium on two sleep responses in the rat have been investigated. The responses observed were sleep latency (the time between drug injection and an observed sleep response) and sleep length (the time between the observed sleep response and arousal). The dosage used was purposely designed to obtain a significant delay between injection and the sleep response. The study was an outgrowth of an attempt to produce, in a minimally distracting environment, a low variability but delayed sleep latency which would be susceptible to systematically introduced environmental sleep distractors. The investigations are a part of a larger programme directed toward determining the environmental antecedents of sleep.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LEVITT, R., WEBB, W. Effect of Pentobarbital Sodium on Sleep Latency and Length of Sleep in the Rat. Nature 204, 605–606 (1964). https://doi.org/10.1038/204605b0
Issue Date:
DOI: https://doi.org/10.1038/204605b0
This article is cited by
-
Effect of amphetamine and pentobarbital on sleep-wake patterns of cats with basal forebrain lesions
Psychopharmacology (1980)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.