Letter | Published:

Toxicity of Whole Tobacco Tar

Nature volume 204, pages 592593 (07 November 1964) | Download Citation

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Abstract

AN experiment was designed to investigate the mortality pattern produced by large doses of tobacco tar in an inbred strain of mice. The object was to find the maximum dose that could evoke a definite carcinogenic response, without causing high mortality. An attempt was also made to investigate the possibility of the development of tolerance to large doses of tobacco tar, by means of varied schedules of administration.

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Affiliations

  1. Department of Experimental Pathology and Cancer Research, School of Medicine, Leeds 2.

    • ANTONIA FLAKS

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DOI

https://doi.org/10.1038/204592a0

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