Letter | Published:

Incorporation of 14C-Glucose and 14C-Glucose 6-phosphate into Glycogen and CO2 by Rat Liver Slices

Nature volume 204, pages 576577 (07 November 1964) | Download Citation

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Abstract

IT has been postulated that the hexokinase reaction is not a necessary step in glycogen synthesis. This is supported by experiments in liver slices1,2 and in the diaphragm3, as well as in cell-free systems4,5. The hexokinase reaction was assumed to occur only in the degradation pathway of glucose, and a different pathway was postulated for glycogen synthesis, circumventing the hexokinase reaction4,5.

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Affiliations

  1. Institute de Química Fisiológica y Patológica, Escuela de Medicina, Universidad de Chile, Borgoño 1470, Santiago, Chile.

    • ENRIQUE FIGUEROA
    •  & ARIANA PFEIFER

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https://doi.org/10.1038/204576a0

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