Abstract
IT has been postulated that the hexokinase reaction is not a necessary step in glycogen synthesis. This is supported by experiments in liver slices1,2 and in the diaphragm3, as well as in cell-free systems4,5. The hexokinase reaction was assumed to occur only in the degradation pathway of glucose, and a different pathway was postulated for glycogen synthesis, circumventing the hexokinase reaction4,5.
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FIGUEROA, E., PFEIFER, A. Incorporation of 14C-Glucose and 14C-Glucose 6-phosphate into Glycogen and CO2 by Rat Liver Slices. Nature 204, 576–577 (1964). https://doi.org/10.1038/204576a0
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DOI: https://doi.org/10.1038/204576a0
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