Abstract
PINEALOMAS have been associated with two endocrine syndromes: destructive, non-parenchymal lesions frequently produce precocious puberty in young boys; true parenchymatous tumours have been found in children with delayed pubescence1. Little is known about the biochemistry of these tumours, or about possible mechanisms by which they exert their pathological effects on gonad function.
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WURTMAN, R., AXELROD, J. & TOCH, R. Demonstration of Hydroxyindole-O-methyl Transferase, Melatonin, and Serotonin in a Metastatic Parenchymatous Pinealoma. Nature 204, 1323–1324 (1964). https://doi.org/10.1038/2041323b0
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DOI: https://doi.org/10.1038/2041323b0
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