Abstract
RECENTLY1 we demonstrated that two substances which we believe to be proteins carry the vitamin B12 in the plasma of normal subjects. These will be referred to as transcobalamin I and II. We then investigated their behaviour in the plasma of patients with chronic myelogenous leukaemia (CML) and found a major abnormality.
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Hall, C. A., and Finkler, A. E., Biochim. Biophys. Acta, 78, 233 (1963).
Pitney, W. R., Beard, M. D., and Van Loon, E. J., J. Biol. Chem., 207, 143 (1954).
Mendelsohn, R. S., Watkin, D. M., Horbett, A. P., and Fahey, J. L., Blood, 13, 740 (1958).
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HALL, C., FINKLER, A. Abnormal Transport of Vitamin B12 in Plasma in Chronic Myelogenous Leukæmia. Nature 204, 1207 (1964). https://doi.org/10.1038/2041207a0
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DOI: https://doi.org/10.1038/2041207a0
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