Abstract
FEW compounds are known to sensitize living organisms to the lethal effects of ionizing radiation. Since those that do include oxygen1 and nitric oxide2,3, both of which are stable free radicals, it was considered of interest to see if certain substituted nitroxides4, which are water-soluble stable free radicals, would exhibit similar properties.
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References
Hollaender, A., Stapleton, G. E., and Martin, G. L., Nature, 167, 103 (1951).
Howard-Flanders, Paul, Advances in Biological and Medical Physics, 6, 553 (Academic Press, New York, 1958).
Dale, W. M., Davies, J. V., and Russel, C., Intern. J. Rad. Biol., 4, 1 (1961).
Hoffmann, A. K., and Henderson, A. T., J. Amer. Chem. Soc., 83, 4671 (1961).
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EMMERSON, P., HOWARD-FLANDERS, P. Sensitization of Anoxic Bacteria to X-rays by Di-t-butyl Nitroxide and Analogues. Nature 204, 1005–1006 (1964). https://doi.org/10.1038/2041005a0
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DOI: https://doi.org/10.1038/2041005a0
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