Abstract
THE question of whether or not exposure to mercury vapour is equivalent to parenteral administration of mercuric ions for tissue accumulation is of great importance when evaluating experimental results for the purpose of setting threshold limits for mercury in ambient air. Clarkson et al.1 showed that mercury vapour is rapidly oxidized to mercury ions in the erythrocytes of the blood.
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References
Clarkson, T. W., Gatzy, J., and Dalton, C., Univ. Rochester AEP Rep., No. 582 (1961).
Hayes, A. D., and Rothstein, A., J. Pharmacol. and Exp. Therapeutics, 138, 1 (1962).
Matthes, F. T., Kirschner, R., Yow, M. D., and Brennan, J. C., Pediatrics, 22, 2, 675 (1958).
Berlin, M., and Ullberg, S., Arch. Environ. Health, 6, 589 (1963).
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BERLIN, M., JOHANSSON, L. Mercury in Mouse Brain after Inhalation of Mercury Vapour and after Intravenous Injection of Mercury Salt. Nature 204, 85–86 (1964). https://doi.org/10.1038/204085a0
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DOI: https://doi.org/10.1038/204085a0
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