Abstract
To my knowledge no method is available for determining the number of antibody-forming cells by simple counting in a hæmocytometer. For this reason the technique proposed here provides possibilities not yet covered by the already known methods for the detection of single antibody-forming cells1–3.
References
Nossal, G. J. V., and Lederberg, J., Nature, 181, 1419 (1958).
Jerne, N. K., and Nordin, A. A., Science, 140, 405 (1963).
Vazquez, J. J., Lab. Invest., 10, 1110 (1961).
Fisher, G. A., Ann. N.Y. Acad. Sci., 76, 673 (1958).
Thorbecke, G. J., and Keuning, F. J., J. Immunol., 70, 129 (1953).
Marshall, A. M. E., and White, R. G., Brit. J. Exp. Path., 42, 379 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ZAALBERG, O. A Simple Method for detecting Single Antibody-forming Cells. Nature 202, 1231 (1964). https://doi.org/10.1038/2021231a0
Issue Date:
DOI: https://doi.org/10.1038/2021231a0
This article is cited by
-
Effect of immune ?sessile? receptors on the choline receptors of the lymphocyte membrane in mice immunized with certain antigens
Bulletin of Experimental Biology and Medicine (1993)
-
Effect of some bacterial antigens on immune receptors of mouse lymphocytes
Bulletin of Experimental Biology and Medicine (1989)
-
Biological activity of thymus preparations from sheep of different ages
Bulletin of Experimental Biology and Medicine (1988)
-
Genetic aspects of the immunomodulationg action of interferon
Bulletin of Experimental Biology and Medicine (1988)
-
Immunomodulating action of interferon in mice with congenital and experimental thymus-dependent immunodeficiency
Bulletin of Experimental Biology and Medicine (1988)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
