Abstract
SEVERAL investigators have attempted to prevent induction of tumours in animals infected by oncogenic viruses using immunization procedures during the latent period, that is, before the appearance of visible (palpable) tumours. In these experiments, virus-infected animals were inoculated during the latent period by live or killed tumour cells or by their components. Zilber and Baidakova1 indicated that the Bittner mammary tumour development in immunized mice could not be prevented although the duration of the latent period was longer. Goldner et al.2 failed to immunize SV40-infected hamsters by ‘Björklund-type’ tumour antigen; some stimulation effect on the tumour growth in such animals was obtained.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Zilber, L. A., and Baidakova, Z. L., Voprosi oncologii, 1, 14 (1955) (in Russian).
Goldner, H., Girardi, A. Y., and Hilleman, M. R., Proc. Soc. Exp. Biol. Med., 114, 2, 456 (1963).
Habel, K., Proc. Soc. Exp. Biol. Med., 106, 4, 722 (1961).
Sjögren, O., Hellström, I., and Klein, G., Cancer Res., 21, 3, 329 (1961).
Defendi, V., Proc. Soc. Exp. Biol. Med., 113, 1, 12 (1963).
Habel, K., and Eddy, B. E., Proc. Soc. Exp. Biol. Med., 113, 1 (1963).
Koch, M. A., and Sabin, A. B., Proc. Soc. Exp. Biol. Med., 113, 1, 4 (1963).
Klein, G., Sjögren, H. O., and Klein, E., Cancer Res., 22, 955 (1962).
Sachs, L., J. Nat. Cancer Inst., 29, 759 (1962).
Prigogina, E. L., and Stavrovskaya, A. A., Nature, 201, 934 (1964).
Evans, C. A., Gorman, L. R., Ito, Y., and Weiser, R. S., J. Nat. Cancer Inst., 29, 277 (1962).
Deichman, G. I., in Symp. Mechanisms of Cancerogenesis, Moscow (January 1964) (in Russian).
Deichman, G. I., and Kluchareva, T. E., Virology (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DEICHMAN, G., KLUCHAREVA, T. Prevention of Tumour Induction in SV40-infected Hamsters. Nature 202, 1126–1128 (1964). https://doi.org/10.1038/2021126b0
Issue Date:
DOI: https://doi.org/10.1038/2021126b0
This article is cited by
-
Serum activity inhibiting specific simian virus 40-induced transplantation resistance and its correlation with primary SV40 tumors appearance in hamsters
Experientia (1978)
-
Effect of BCG and Allogeneic Tumour Cells on Adenovirus Type 12 Tumorigenesis in Mice
Nature (1969)
-
Immunological relationships of some oncogenic DNA viruses
Archiv f�r die gesamte Virusforschung (1969)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
