Abstract
HAPTEN conjugates of poly-L-lysine are antigenic in about 25 per cent of random bred Hartley guinea pigs and in 100 per cent of the highly inbred strain 2 guinea pigs provided that the conjugates are not too highly coupled1–3. This communication compares the antigenicity of lightly coupled benzylpenicilloyl conjugates of poly-D-lysine and of poly-L-lysine in strain 2 guinea pigs. Parker and Thiel4 have recently reported, in abstract, that a lightly coupled benzylpenicilloyl conjugate of poly-D-lysine was non-antigenic in 35 random-bred guinea pigs.
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LEVINE, B. Antigenicity of Hapten Conjugates of Poly-D-lysine and of Poly-L-lysine in Strain 2 Guinea Pigs. Nature 202, 1008–1009 (1964). https://doi.org/10.1038/2021008a0
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DOI: https://doi.org/10.1038/2021008a0
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