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Preparation of Very High Specific Activity Iododeoxyuridine, lodouridine and lodouracil, labelled with Iodine-125, -131 or -132

Abstract

As part of a contribution to a study of the relative merits of radioactive substances used for brain tumour1 localization we were asked to prepare 131I-5-iododeoxy-uridine of very high specific activity (of the order of 100 µc./µg) and in a solution suitable for injection into rats.

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References

  1. Matthews, C. M. E., and Molinaro, G., Brit. J. Exp. Path., 44, 260 (1963).

    CAS  Google Scholar 

  2. Prusoff, W. H., Biochim. Biophys. Acta, 32, 295 (1959).

    Article  CAS  Google Scholar 

  3. Prusoff, W. H., Holmes, W. L., and Welch, A. D., Cancer Res., 13, 221 (1953).

    CAS  PubMed  Google Scholar 

  4. Myers, W. G., and Vanderleeden, J. C., J. Nuclear Med., 1, 149 (1960).

    CAS  Google Scholar 

  5. Reith, W. S., and Tampion, W., Nature, 197, 180 (1963).

    Article  ADS  CAS  Google Scholar 

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SILVESTER, D., WHITE, N. Preparation of Very High Specific Activity Iododeoxyuridine, lodouridine and lodouracil, labelled with Iodine-125, -131 or -132. Nature 200, 65–66 (1963). https://doi.org/10.1038/200065a0

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  • DOI: https://doi.org/10.1038/200065a0

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