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Occurrence of Two Different Enzymes in the Silkworm, Bombyx mori, to reduce Folate and Sepiapterin

Naturevolume 199pages908909 (1963) | Download Citation



THE mutant lemon of the silkworm is characteristically yellow in colour, accumulating a fluorescent pigment, xanthopterin-B1, in the skin. Extract of the fat body of the wild-type silkworm converts this pigment into a non fluorescent product1. There is some evidence to support the view that xanthopterin-B1 is identical with sepiapterin2, which is known to be reduced, in the presence of reduced nicotinamide dinucleotide phosphate (NADPH), by a folate reductase from chicken liver and Drosophila3,4.

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    Aruga, H., Kawase, S., and Akino, M., Experientia, 10, 336 (1954).

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    Nawa, S., and Taira, T., Proc. Jap. Acad., 30, 632 (1954).

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    Taira, T., Nature, 189, 231 (1961).

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    Taira, T., Jap. J. Genet., 36, 244 (1961).

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    Akino, M., and Tsusue, M. (unpublished work).

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    Zakrzewski, S. F., J. Biol. Chem., 235, 1776 (1960).

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    Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

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  1. Department of Biology, Metropolitan University, Tokyo

    •  & MIKI AKINO


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