Letter | Published:

Study of Several Gene Frequencies in Yugoslav Population

Naturevolume 199pages830831 (1963) | Download Citation



RECENT years have witnessed a rather rapid development of the population genetics of certain hereditary characters in man. Its findings are based mostly on the analyses of material obtained from voluntary blood donors1–3. This method of collecting research material has numerous advantages, but also several marked disadvantages. For example, data on the frequency of hereditary characters are mostly limited to the antigen properties of red blood cells2. The value of work in population genetics increases with the number of analysed genes from a certain population sample. Some of the genes being factors of marked polymorphism in man, their frequency can lead us to remote ancestors, and genes can serve as markers in the study of linkage in the chromosomes in man, where the need for just such markers is felt most acutely4.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Boyd, W. C., Tabulae Biologicae, 17, 113 (1939).

  2. 2

    Mourant, A. E., The Distribution of the Human Blood Groups (Blackwell Sci. Pub., Oxford, 1954).

  3. 3

    Race, R. R., and Sanger, R., Blood Groups in Man, third ed. (Blackwell Sci. Pub., Oxford, 1958).

  4. 4

    Allison, A. C., Amer. Nat., 93, 5 (1959).

  5. 5

    Bhende, Y. M., Deshpande, C. K., Bhatia, H. M., Sanger, R., Race, R. R., Morgan, W. T. J., and Watkins, W. M., Lancet, i, 903 (1952).

  6. 6

    Ceppellini, R., Nasso, S., and Tecilazich, F., La malattia Emolitica del Neonato (Istituto Sieroterapico, Milanese Serafino Belfanti, Milano, 1952).

  7. 7

    Levine, P., Robinson, E., Celano, M., Briggs, O., and Falkinburg, L., Blood, 10, 1100 (1955).

  8. 8

    McConnell, R. B. (personal communication, 1960).

  9. 9

    Harris, H., and Kalmus, H., Ann. Eugen. (Lond.), 15, 24 (1949).

  10. 10

    Smithies, O., Biochem. J., 71, 585 (1959).

  11. 11

    Grünwald, P., Second Intern. Conf. Hum. Genet. (Abst.), Rome (1961).

  12. 12

    Polak, A., Acta Med. Jug., 8, 177 (1954).

  13. 13

    Pfeifer, S., and Lukovič, G., Rad. knj., 323, 225 (Jazu, Zagreb, 1961).

  14. 14

    Baitsch, H., Liebrich, K. G., Pinkerton, F. J., and Marmond, L. E., Second Intern. Conf. Hum. Genet. (Abst.), Rome (1961).

  15. 15

    Pfeifer, S., and Grünwald, P., II. Jug. simp. end. guš., 267 (Komnis, Zagreb, 1961).

  16. 16

    Grünwald, P., and Herman, Č., Nature, 194, 95 (1962).

  17. 17

    Grünwald, P., and Pfeifer, S., Lij. vj., 84, 27 (1962).

  18. 18

    Sutton, H. E., Matson, G. A., Robinson, A. R., and Koucky, R. W., Amer. J. Hum. Genet., 12, 338 (1960).

  19. 19

    Baitsch, H., Meier, G., Schoeller, L., and Kahlich-Koenner, D. M., Nature, 186, 976 (1960).

  20. 20

    Murawski, K., and Miszcak, T., Science, 133, 1427 (1961).

  21. 21

    Penrose, L. S., in Natural Selection in Human Population (Pergamon Press, London, 1959).

Download references

Author information


  1. Department of Biology, Medical Faculty, University of Zagreb



  1. Search for PETAR GRÜNWALD in:

  2. Search for ČEDOMIL HERMAN in:

About this article

Publication history

Issue Date




By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.