Letter | Published:

Effect of Multiple Injections of Calcium Compounds on the Survival of X-irradiated Rats

Naturevolume 199pages821822 (1963) | Download Citation



A MODERATE increase in the survival of X-irradiated rats has been observed when either parathyroid extract or ethylenediamine tetraacetate (EDTA) was injected before or after mid-lethal doses of X-rays1–3. The action of these substances has been attributed to bone resorption, which was thought to protect the adjacent radiosensitive bone marrow by exposing it to an increased concentration of newly-released calcium. In the work recorded here, we have tested this view directly by the injection of calcium compounds.

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    Present address: Biologie, Euratom (C.C.R.), Ispra, Italy


  1. Biology Branch, Division of Biology and Health Physics, Atomic Energy of Canada, Ltd., Chalk River, Ontario

    • R. H. RIXON
    •  & J. F. WHITFIELD


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