Letter | Published:

Sex Differences in the Serum Cholesterol Response to Stress in Monkeys


THE investigation reported here was undertaken as an initial step in the assessment of central nervous system influences on the transport of serum lipids, with particular reference to their possible role in the pathogenesis of atherosclerosis. The experimental situation dictated that monkeys be moderately restrained for extended periods of time in order that the neural variables could be manipulated under controlled conditions. It became apparent, however, that such restraint itself was a significant variable affecting the level of cholesterol and other lipids in the serum, hence this study was designed to investigate this aspect of the problem in a detailed fashion.

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