Letter | Published:

Effect of Orotic Acid on the Synthesis of Citrovorum Factor and of Methionine in Liver of the Chick

Naturevolume 199pages695696 (1963) | Download Citation

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Abstract

IN a dietary condition in which only B12 of the vitamins and methionine of the amino-acids are active for growth in the chick, it has been demonstrated that orotic acid is a growth factor1. One biochemical hypothesis on the effect of orotic acid in B12 and methionine deficiency is that orotic acid acts in the metabolism of the 1–C unit.

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References

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  1. Istituto di Chimica biologica dell' Universitá di Bologna

    • GIOVANNI MORUZZI
    • , MARIO MARCHETTI
    •  & ROMANO VIVIANI

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https://doi.org/10.1038/199695a0

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