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Effect of Orotic Acid on the Synthesis of Citrovorum Factor and of Methionine in Liver of the Chick

Nature volume 199, pages 695–696 (1963)Cite this article

Abstract

IN a dietary condition in which only B12 of the vitamins and methionine of the amino-acids are active for growth in the chick, it has been demonstrated that orotic acid is a growth factor1. One biochemical hypothesis on the effect of orotic acid in B12 and methionine deficiency is that orotic acid acts in the metabolism of the 1–C unit.

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References

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Authors and Affiliations

  1. Istituto di Chimica biologica dell' Universitá di Bologna,

    GIOVANNI MORUZZI, MARIO MARCHETTI & ROMANO VIVIANI

Authors
  1. GIOVANNI MORUZZI
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  2. MARIO MARCHETTI
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  3. ROMANO VIVIANI
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MORUZZI, G., MARCHETTI, M. & VIVIANI, R. Effect of Orotic Acid on the Synthesis of Citrovorum Factor and of Methionine in Liver of the Chick. Nature 199, 695–696 (1963). https://doi.org/10.1038/199695a0

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