Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Structure Of Hæemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Perutz, M. F., Rossmann, M. G., Cullis, A. F., Muirhead, H., Will, G., and North, A. C. T., Nature, 185, 416 (1960).

    Article  ADS  CAS  Google Scholar 

  2. Kendrew, J. C., Dickerson, R. E., Strandberg, B. E., Hart, R. G., Davies, D. R., Phillips, D. E., and Shore, V. C., Nature, 185, 422 (1960).

    Article  ADS  CAS  Google Scholar 

  3. Haurowitz, F., Hoppe-Seyl. Z., 254, 266 (1938).

    Article  CAS  Google Scholar 

  4. Benesch, R., and Benesch, R. E., J. Mol. Biol., 6, 498 (1963).

    Article  CAS  Google Scholar 

  5. Bragg, W. L., and Perutz, M. F., Acta Cryst., 5, 323 (1952).

    Article  CAS  Google Scholar 

  6. Jope, H. M., and O'Brien, J. R. P., in Haemoglobin, p. 269, edit. by Roughton, F. J. W., and Kendrew, J. C., (Butterworths, London, 1949).

    Google Scholar 

  7. Perutz, M. F., Trotter, I. F., Howells, E. R., and Green, D. W., Acta Cryst., 8, 241 (1955).

    Article  CAS  Google Scholar 

  8. Braunitzer, G., Gehring-Müller, R., Hilschmann, N., Hilse, K., Hobom, G., Rudloff, V., and Wittmann-Liebold, B., Hoppe-Seyl. Z., 325, 283 (1961).

    Article  CAS  Google Scholar 

  9. Braunitzer, G., Rudloff, V., and Hilschmann, N., Hoppe-Seyl. Z., 331, 1 (1963).

    Article  CAS  Google Scholar 

  10. Konigsberg, W., Guidotti, G., and Hill, R. J., J. Biol Chem., 236, PC 55 (1961).

    Google Scholar 

  11. Konigsberg, W., and Hill, R. J., J. Biol. Chem., 237, 3157 (1962).

    CAS  PubMed  Google Scholar 

  12. Perutz, M. F., and Mazzarella, L. (see following article).

  13. Broad, D. A. G., Patent Applications Nos. 5172, 5173, 12761, 38939, 10984 and 13376 (1956).

  14. Cecil, R., and Snow, N. S., Biochem. J., 82, 247 (1962).

    Article  CAS  Google Scholar 

  15. Blow, D. M., Proc. Roy. Soc., 247, 302 (1958).

    Article  ADS  CAS  Google Scholar 

  16. Blow, D. M., and Rossmann, M. G., Acta Cryst., 14, 1195 (1961).

    Article  CAS  Google Scholar 

  17. Blow, D. M., and Crick, F. H. C., Acta Cryst., 12, 794 (1959).

    Article  CAS  Google Scholar 

  18. Cullis, A. F., Muirhead, H., Perutz, M. F., Rossmann, M. G., and North, A. C. T., Proc. Roy. Soc., A, 265, 15 (1961).

    Article  ADS  CAS  Google Scholar 

  19. Kendrew, J. C., Watson, H. C., Strandberg, B. E., Dickerson, R. E., Phillips, D. C., and Shore, V. C., Nature, 190, 663 (1961).

    Article  ADS  Google Scholar 

  20. Ingram, D. J. E., Gibson, J. F., and Perutz, M. F., Nature, 178, 905 (1956).

    Article  ADS  CAS  Google Scholar 

  21. Braunitzer, G., and Matsuda, G., J. Biochem., 53, 262 (1963).

    Article  CAS  Google Scholar 

  22. Smith, D. B. (private communication).

  23. Antonini, A., Wyman, J., Moretti, R., and Rossi-Fanelli, A., Biochim. Biophys. Acta, 71, 124 (1963).

    Article  CAS  Google Scholar 

  24. Monod, J., Changeux, J.-P., and Jacob, F., J. Mol. Biol., 6, 306 (1963).

    Article  CAS  Google Scholar 

  25. Koshland, D. E., Gerhart, J. C., and Pardee, A. B. ; Greundlich, M., and Umbarger, H. E., Cold Spring Harbor Symp. Quant. Biol., 28 (in the press).

  26. Perutz, M. F., Nature, 194, 914 (1962).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MUIRHEAD, H., PERUTZ, M. Structure Of Hæemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution. Nature 199, 633–638 (1963). https://doi.org/10.1038/199633a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/199633a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing