Letter | Published:

Possible Turnover of DNA with an Increased 6-Methylaminopurine Content

Naturevolume 199pages599600 (1963) | Download Citation

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Abstract

THE 6-methylaminopurine content of the DNA of a thymine-requiring mutant of E. coli strain 15, normally 2.1 per cent of the adenine, increases when 5-aminouracil is added to a logarithmically growing culture1. We have previously reported that the 6-methylaminopurine content of the DNA of a culture of a similar strain (strain I) continues to increase after net DNA synthesis ceases2. We have also shown that this increase could not be attributed to additions to the ends of DNA molecules since 6-methylaminopurine was not localized at these ends2.

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References

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Affiliations

  1. Department of Biochemistry, College of Physicians and Surgeons, Columbia University, New York, 32

    • ELIZABETH C. THEIL
    •  & STEPHEN ZAMENHOF

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https://doi.org/10.1038/199599a0

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