Letter | Published:

A Postulated Biosynthesis of Some ‘Anomalous’ Natural Phenolic Compounds

Naturevolume 199pages592593 (1963) | Download Citation

Subjects

Abstract

CONSIDERABLE experimental evidence has been provided in recent years to substantiate Birch's biogenetic proposals1 for the polyacetate derivation of a number of classes of naturally occurring phenolic compounds. However, certain phenolic substances are known which, although ‘acetate-derived’, cannot be formulated directly via a linear polyketide chain. Included in this ‘anomalous’ category are sulochrin (4), citromycetin (1), fulvic acid (3), and pinselic acid (2). To rationalize the structures of these compounds, Birch1 and Thomas2 have each postulated a branched polyketide precursor.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Birch, A. J., Fortschr. Chem. Org. Naturstoffe, 14, 186 (1957); Proc. Chem. Soc., 3 (1962).

  2. 2

    Thomas, R., Biochem. J., 78, 748 (1961).

  3. 3

    Gatenbeck, S., Svensk Kem. Tidskr., 72, 188 (1960).

  4. 4

    Stickings, C. E., and Mahmoodian, A., Chem. and Indust., 1718 (1962).

  5. 5

    cf. Whalley, W. B., in Recent Developments in the Chemistry of Natural Phenolic Compounds, edit. by Ollis, W. D., 49 (Pergamon Press, 1961).

  6. 6

    Loudon, J. D., in Progress in Organic Chemistry, 5, 60 (Butterworths, 1961); cf. Davies, A. C., Organic Peroxides, 143 (Butterworths, 1961).

  7. 7

    Bedford, C. T., and Money, T. (unpublished results).

Download references

Author information

Affiliations

  1. Department of Chemistry, University of Glasgow

    • T. MONEY

Authors

  1. Search for T. MONEY in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/199592a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.