Letter | Published:

Assessment of Functional Competence in Isolated Muscular Tissues

Naturevolume 199pages494495 (1963) | Download Citation

Subjects

Abstract

IN order to test for functional competence in thin pieces of isolated tissue containing muscular elements, such as the skin of the rat (which contains smooth muscle and a sheet of skeletal muscle known as the panniculus carnosus)', a bath was devised in which the muscles could be excited directly or indirectly by transmural stimulation1. The response of the stimulated muscle provided a measure of functional competence in the surviving tissue. This bath and also our method of recording the pressure changes developed in it are described here.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Hellmann, K., J. Physiol. (Lond.) (in the press).

  2. 2

    Hellmann, K., Brit. J. Pharmacol. (in the press).

  3. 3

    Paton, W. D. M., J. Physiol. (Lond.), 127, 40, P (1955).

  4. 4

    Hellmann, K., J. Physiol. (Lond.), 165, 11, P (1963).

  5. 5

    Hellmann, K., J. Physiol. (Lond.) (in the press).

Download references

Author information

Affiliations

  1. Chemotherapy Unit, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, W.C.2

    • K. HELLMANN
    • , J. A. STEDMAN
    •  & D. I. DUKE

Authors

  1. Search for K. HELLMANN in:

  2. Search for J. A. STEDMAN in:

  3. Search for D. I. DUKE in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/199494a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.