Letter | Published:

Isolation of Phosvitin from the Plasma of the Œstrogenized Immature Pullet

Naturevolume 199page487 (1963) | Download Citation



THE presence of phosphoprotein in the plasma of the laying hen is widely held to be the result of the action of œstrogenic substances produced by the growing ova of the mature bird1, though the precise nature and quantities of œstrogenic substances present in the blood stream have not yet been determined. Recently it has been shown that the phosphoprotein in the plasma of the laying hen is phosvitin, the principal protein of egg yolk2, and it seemed desirable to examine the plasma of œstrogen-treated non-laying birds to determine whether or not such treatments could, in fact, lead to the formation of phosvitin.

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  1. 1

    Sturkie, P. D., Avian Physiology (Comstock Publishing Assoc., Ithaca. New York, 1954).

  2. 2

    Heald, P. J., and McLachlan, P. M., Biochem. J., 87, 571 (1963).

  3. 3

    Connelly, C., and Taborsky, G., J. Biol. Chem., 236, 1364 (1961).

  4. 4

    Mecham, D. K., and Olcott, H. S., J. Amer. Chem. Soc., 71, 3670 (1949).

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  1. Twyford Laboratories, Ltd., Twyford Abbey Road, London, N.W.10

    • P. J. HEALD
    •  & P. M. McLACHLAN


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