Abstract
IN recent years ultrasonic energy has been used in the extraction of various materials from plants, animals, and micro-organisms for biochemical analysis1. The application of ultrasound has proved advantageous for the isolation of enzymes, nucleic acids, and other heat-labile substances from cells and tissues. Moreover, ultrasonic energy has been used widely for various industrial applications to facilitate the extraction of commercially important substances2. The increasing use of ultrasonic instruments in extraction processes is based on the observations that: (1) disruption of cells is rapid; (2) the extraction process is accelerated; (3) the yield of extract usually is increased; (4) the use of ultrasonic energy permits the extraction of certain materials otherwise not readily obtainable.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Fry, W. G., Advances Biol. Med. Phys., 4, 282 (1958).
Schroder, G. W., Food Eng., 25, 48 (1953). Babikov, I. O., Ultrasound and its Industrial Applications (Consultants Bureau, New York, 1960).
Hughes, D. E., and Nyborg, W. L., Science, 138, 108 (1962).
Thompson, D., and Vilbrandt, F. C., Indust. Eng. Chem., 46, 1172 (1954). Vigoureux, P., Ultrasonics (Wiley, New York, 1951).
Lott, J. A., thesis, Rutgers University (1961).
DeMaggio, A. E., J. Pharm. Sci., 50, 676 (1961). DeMaggio, A. E., and King, L. D., ibid., 50, 341 (1961).
Lott, J. A., and DeMaggio, A. E., Science, 139, 825 (1963).
United States Pharmacopeia (Mack, Rev. 16, Easton, Penn., 1960).
Nyborg, W. L., in Ultrasound in Biology and Medicine (A.I.B.S., Washington, D.C., 1957).
Head, W. F., jun., Beal, H. M., Lauter, W. M., J. Amer. Pharm. Assoc., Sci. Ed., 45, 239 (1956). Wray, P. E., and Small, L. D., ibid., 47, 823 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DEMAGGIO, A., LOTT, J. & GERRAUGHTY, R. Isolation of Alkaloids using Ultrasonic Energy. Nature 199, 1292–1293 (1963). https://doi.org/10.1038/1991292a0
Issue Date:
DOI: https://doi.org/10.1038/1991292a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
