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An Analysis of Adenovirus Particles and Soluble Antigens produced in the Presence of 5-Bromodeoxyuridine

Nature volume 199, pages 12101211 (21 September 1963) | Download Citation

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Abstract

THE addition of 30 µg/ml. of 5-bromodeoxyuridine (BUDR) to HeLa cell cultures infected with adenovirus type 5 results in a marked inhibition of the synthesis of infectious virus, but does not prevent the development of cytopathic effect nor the formation of complement-fixing antigen1.

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Author information

Author notes

    • L. KJELLÉN

    Permanent address: Malmö Allmänna Sjukhus, Malmö, Sweden.

Affiliations

  1. National Institute for Medical Research, Mill Hill, London, N.W.7.

    • L. KJELLÉN
    • , H. G. PEREIRA
    • , R. C. VALENTINE
    •  & J. A. ARMSTRONG

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DOI

https://doi.org/10.1038/1991210a0

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