Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

An Analysis of Adenovirus Particles and Soluble Antigens produced in the Presence of 5-Bromodeoxyuridine

Nature volume 199, pages 1210–1211 (1963)Cite this article

Abstract

THE addition of 30 µg/ml. of 5-bromodeoxyuridine (BUDR) to HeLa cell cultures infected with adenovirus type 5 results in a marked inhibition of the synthesis of infectious virus, but does not prevent the development of cytopathic effect nor the formation of complement-fixing antigen1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Kjellén, L., Virology, 18, 64 (1962).

    Article  Google Scholar 

  2. Pereira, H. G., Allison, A. C., and Farthing, C. P., Nature, 183, 895 (1959).

    Article  ADS  CAS  Google Scholar 

  3. Klemperer, H. G., and Pereira, H. G., Virology, 9, 536 (1959).

    Article  CAS  Google Scholar 

  4. Pereira, H. G., Virology, 6, 601 (1958).

    Article  CAS  Google Scholar 

  5. Gessler, A. E., Bender, C. E., and Parkinson, M. C., Trans. N.Y. Acad. Sci., 18, 701 (1956).

    Article  CAS  Google Scholar 

  6. Pereira, H. G., and Valentine, R. C., J. Gen. Microbiol., 19, 178 (1958).

    Article  CAS  Google Scholar 

  7. Pereira, H. G., and de Figueiredo, M. V. T., Virology, 18, 1 (1962).

    Article  CAS  Google Scholar 

  8. Kohn, J., Nature, 183, 1055 (1959).

    Article  ADS  CAS  Google Scholar 

  9. Watson, D. H., Biophys. Biochim. Acta, 61, 321 (1962).

    CAS  Google Scholar 

  10. Kozinski, A. W., and Szybalski, W., Virology, 9, 260 (1959).

    Article  CAS  Google Scholar 

  11. Djordjevic, B., and Szybalski, W., J. Exp. Med., 112, 509 (1960).

    Article  CAS  Google Scholar 

  12. Greer, S., J. Gen. Microbiol., 22, 618 (1960).

    Article  CAS  Google Scholar 

  13. Kaplan, H. G., Smith, K. C., and Tolmin, P., Nature, 190, 794 (1961).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Institute for Medical Research, Mill Hill, London, N.W.7

    L. KJELLÉN, H. G. PEREIRA, R. C. VALENTINE & J. A. ARMSTRONG

  2. Malmö Allmänna Sjukhus, Malmö, Sweden

    L. KJELLÉN

Authors
  1. L. KJELLÉN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. G. PEREIRA
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. C. VALENTINE
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. A. ARMSTRONG
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

KJELLÉN, L., PEREIRA, H., VALENTINE, R. et al. An Analysis of Adenovirus Particles and Soluble Antigens produced in the Presence of 5-Bromodeoxyuridine. Nature 199, 1210–1211 (1963). https://doi.org/10.1038/1991210a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1991210a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing