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Effects of Lysergic Acid Diethylamide on the Total Leukocytes and Eosinophils of the Female Rat

Nature volume 199, pages 11941195 (21 September 1963) | Download Citation

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Abstract

THE hallucinogenic drug, lysergic acid diethylamide (LSD-25), produces in minute doses marked aberrations in mental functions. The psychic symptoms of LSD-25 intoxication resemble aspects peculiar to schizophrenia1,2. As a result, the drug has been utilized as an effective tool to explore the induction of reversible psychoses in non-psychotic subjects. It has been assumed that the similarities produced by LSD-25 could yield information pertinent to the mechanisms and pathophysiology involved in schizophrenia2,3.

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Affiliations

  1. Laboratories for Therapeutic Research, Research Institute of the Brooklyn College of Pharmacy, Long Island University, Brooklyn, New York.

    • A. M. SACKLER
    • , A. S. WELTMAN
    •  & S. B. SPARBER

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https://doi.org/10.1038/1991194a0

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