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Influence of Calcium Phosphate on the Absorption of Radioactive Strontium

Abstract

IT has been found, in experiments which will be reported more fully elsewhere, that rats which are fasted before and after the intragastric administration of a solution containing strontium-85 absorb about three times as much of the strontium as rats with free access to the stock diet. It has also been found that when the stock diet is restored immediately after the administration of strontium-85 to fasted rats, the fraction of the dose absorbed is no greater than for fed rats. This effect is due mainly to one component of the diet, namely bone-meal. Calcium hydrogen phosphate mixed with cellulose and moistened with a solution of sucrose also reduces absorption when given to fasted rats after the strontium has been administered (Table 1).

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References

  1. Macdonald, N. S., Spain, P. C., Ezmirlian, F., and Rounds, D. E., J. Nutr. 57, 555 (1955).

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BRUCE, R. Influence of Calcium Phosphate on the Absorption of Radioactive Strontium. Nature 199, 1107–1108 (1963). https://doi.org/10.1038/1991107a0

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