Letter | Published:

A Fatal Case of Poisoning with Amitriptyline

Naturevolume 199pages11031104 (1963) | Download Citation



NEW psychopharmacological drugs bring relief to many patients. However, their misuse can result in misadventures which may even be fatal. Several reports1 already document this fact, despite the wide margin of safety these drugs have. This note reports a fatal episode involving amitriptyline, another new drug in the fast growing list.

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    Obersteg, J. Im, and Bäumler, J., Acta med. et leg. (in the press). Wütschke, J., Arch. Tox., 18, 275 (1960).

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    Douglas, A. D. M., and Bates, T. J. N., Brit. Med. J., i, 1514 (1957). Sacks, N. Z., Lancet, i, 983 (1957).

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    Hermann, B., and Pulver, R., Arch. Intern. Pharmacodyn., 126, 454 (1960). Lancaster, N. P., and Forster, A. R., Brit. Med. J., ii, 1458 (1959). Obersteg, J. Im, and Bäumler, J., Arch. Tox, 19, 339 (1962).

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    Adlin, E. V., Amer. Med. Assoc. Arch. Intern. Med., 102, 484 (1958). Cillius, A. J., Med. Proc., 6, 93 (1960) Bäumler, J., Gander, V., and Obersteg, J. Im, Beiträge zur gerichtlichen Medizin, 22, 10 (1963).

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  1. Western Reserve University, School of Medicine, Cleveland, Ohio

  2. Institute of Legal Medicine, University of Basle



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