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Properties of a Carrier System to transport L–Dopa into Brain Slices

Abstract

L-DOPA(DIHYDROXYPHENYLALANINE) is accumulated in brain cortex slices of guinea pigs against a concentration gradient when the slices are incubated in glucose Ringer at 37° C. The accumulation is reduced by anaerobic condition and by addition of metabolic inhibitors.

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YOSHIDA, H., KANIIKE, K. & NAMBA, J. Properties of a Carrier System to transport L–Dopa into Brain Slices. Nature 198, 191–192 (1963). https://doi.org/10.1038/198191a0

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