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Mutation and Recombination of Flagellar Antigen i of Salmonella typhimurium

Abstract

CHANGES in the flagellar antigenic constitution of many Salmonella species have been reported1; but their genetical basis is unknown. As the flagellar antigen is a protein, flagellin, the commonest kind of mutational change in it is presumably alteration of a single amino-acid, which would perhaps cause only a minor change in its serological character. We now report a serological and genetical investigation of mutants of S. typhimurium with slightly altered forms of the phase 1 flagellar antigen i.

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JOYS, T., STOCKER, B. Mutation and Recombination of Flagellar Antigen i of Salmonella typhimurium. Nature 197, 413–414 (1963). https://doi.org/10.1038/197413a0

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