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An Uncommon Blood Group Isoantibody (Anti-M) in Neoplastic Disease

Abstract

THE first case in this series of anti-M sensitized patients was reported in 1958 because it presented a unique exception to the generalization that cold agglutinins are without significance in transfusion practice. The patient had received no M stimulus from either previous transfusion or pregnancy. We commented: “The possibility of a relation between the abnormal isoantibody and the patient's carcinoma of the cecum is being investigated”1.

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References

  1. Reilly, E. B., Klein, S. J., and Matsushima, J. J., Amer. J. Clin. Path., 30, 384 (1958).

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  2. Race, R. R., and Sanger, R., Blood Groups in Man, 256 (Charles C. Thomas, Springfield, 1959). Kabat, E. A., Blood Group Substances, 113 (Academic Press, New York, 1956).

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KLEIN, S., REILLY, E. & MATSUSHIMA, J. An Uncommon Blood Group Isoantibody (Anti-M) in Neoplastic Disease. Nature 197, 393–394 (1963). https://doi.org/10.1038/197393a0

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