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Erythropoietic Stimulation in the Hypertransfused Guinea-Pig following Injections of Human Urinary Erythropoietin

Nature volume 196, pages 279–280 (1962)Cite this article

Abstract

CONSIDERABLE evidence has accumulated in recent years that supports the concept of a humoral component as part of the mechanism for control of erythropoiesis. The humoral agent has been termed erythropoietin or erythropoietic stimulating factor, and has been obtained from plasma and urine of various anæmic animals and from urine of patients with various hæmatological disorders. Erythropoietin does not appear to be species specific; thus, human, rabbit and sheep erythropoietin stimulate erythropoiesis in the mouse, rat and rabbit.

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References

  1. Gordon, A. S., Ciba Found. Symp. Hæmopoiesis, 325 (J. and A. Churchill, Ltd., London, 1960).

  2. Osmond, D. G., Ciba Found. Symp. Hæmopoiesis, 363 (J. and A. Churchill, Ltd., London, 1960).

  3. Osmond, D. G., Roylance, P. J., Yoffey, J. M., and Van Dyke, D. C., Brit. J. Hæmat., 7, 281 (1961). Yoffey, J. M., Quantitative Cellular Hæmatology, 52 (Charles C. Thomas, Springfield, Ill., 1960).

    Google Scholar 

  4. Van Dyke, D. C., Ciba Found. Symp. Hæmopoiesis, 364 (J. and A. Churchill, Ltd., London, 1960).

  5. Borsook, H., The Kinetics of Cellular Proliferation, 358 (Grune and Stratton, New York, 1959).

    Google Scholar 

  6. Garcia, J. F., and Van Dyke, D. C., J. App. Physiol., 14, 233 (1959).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Donner Laboratory, University of California Lawrence Radiation Laboratory, Berkeley

    JOSEPH F. GARCIA & JOHN C. SCHOOLEY

Authors
  1. JOSEPH F. GARCIA
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  2. JOHN C. SCHOOLEY
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GARCIA, J., SCHOOLEY, J. Erythropoietic Stimulation in the Hypertransfused Guinea-Pig following Injections of Human Urinary Erythropoietin. Nature 196, 279–280 (1962). https://doi.org/10.1038/196279a0

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  • DOI: https://doi.org/10.1038/196279a0

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