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Dermal Elastin in Actinic Elastosis and Pseudoxanthoma Elasticum

Nature volume 195, pages 716–717 (1962)Cite this article

Abstract

FOR sixty-five years the identity of the fibres staining with elastic tissue stains in actinic (senile) elastosis has been the subject of debate1–5. Recent work has shown that elastotic dermis contains more hexosamine and less hydroxyproline than covered skin and that these changes are localized in the upper dermis6. This communication describes the estimation of elastin from elastotic skin determined after extraction in hot alkali7.

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Author information

Authors and Affiliations

  1. Division of Dermatology, Department of Medicine, Department of Biochemistry, and Center for the Study of Aging, Duke University Medical Center, Durham, North Carolina

    J. GRAHAM SMITH JUN., EUGENE A. DAVIDSON & RICHARD D. CLARK

Authors
  1. J. GRAHAM SMITH JUN.
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  2. EUGENE A. DAVIDSON
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  3. RICHARD D. CLARK
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SMITH, J., DAVIDSON, E. & CLARK, R. Dermal Elastin in Actinic Elastosis and Pseudoxanthoma Elasticum. Nature 195, 716–717 (1962). https://doi.org/10.1038/195716a0

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