Abstract
PORTERFIELD1 recommended the use of goose red blood cells for hæmagglutination and hæmagglu-tination inhibition (H.A.I.) tests with arborvirus antigens. Such tests are susceptible to non-specific inhibition by lipids present in normal animal serum2,3. These non-specific inhibitors are widely distributed4, but little is known of their nature or mode of action.
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References
Porterfield, J. S., Nature, 180, 1201 (1957).
Channock, R. M., and Sabin, A. B., J. Immunol., 73, 338 (1954).
Clarke, D. H., and Casals, J., Amer. J. Trop. Med. Hyg., 7, 561 (1958).
Salminen, A., Acta Virologica 4, 17 (1960).
Porterfield, J. S., and Rowe, C. E., Virology, 2, 765 (1960).
Williams, H., and Thorburn, H., J. Hyg. (Camb.), 59, 437 (1961).
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WILLIAMS, H., THORBURN, H. Use of Goose Cells in Hæmagglutination Tests with Louping ill Virus Antigen. Nature 195, 520–521 (1962). https://doi.org/10.1038/195520b0
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DOI: https://doi.org/10.1038/195520b0
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