Abstract
THE effects of the inhalation of oxygen at greater than normal pressures have assumed greater importance as man's penetration into the depths of the sea has increased. It was Bert1 who for the first time revealed that, although oxygen at low pressures sustains life, the gas is toxic at high pressures. In their review of the subject, Stadie et al.2 conclude that the dominant symptoms of the action of oxygen at 0.8–2.0 atmospheres are respiratory, while at higher oxygen pressures central nervous system symptoms predominate. Several theories have been put forward to explain the toxic effects of oxygen at high pressures3, but no one theory is completely satisfactory.
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WOOD, J., WATSON, W. Protective Action of γ-Aminobutyric Acid against Oxygen Toxicity. Nature 195, 296 (1962). https://doi.org/10.1038/195296a0
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DOI: https://doi.org/10.1038/195296a0
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