Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Effect of Salicylate on Plasma Magnesium-Levels


IN this laboratory a recent examination of the distribution of electrolytes in rats following the repeated administration of both sodium and potassium salicylate has shown that a marked decrease in the excretion of urinary magnesium occurs. Evidence of a less well-defined increase in the level of plasma magnesium was also found1.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Charnock, J. S., Opit, L. J., and Hetzel, B. S., Metabolism (Nov. 1961).

  2. 2

    Seeburg, V. P., Hansen, D., and Whitney, B., J. Pharmacol. Exp. Therap., 101, 275 (1951).

    Google Scholar 

  3. 3

    Orange, M., and Rhein, H. C., J. Biol. Chem., 189, 379 (1951).

    CAS  PubMed  Google Scholar 

  4. 4

    Trinder, P., Biochem. J., 57, 301 (1954).

    CAS  PubMed  PubMed Central  Article  Google Scholar 

  5. 5

    Winter, J. E., and Barbour, H. G., Proc. Soc. Exp. Biol. Med., 25, 587 (1928).

    CAS  Article  Google Scholar 

  6. 6

    Sollman, T., Manual of Pharmacology, eighth ed. (W. B. Saunders and Co., 1957).

    Google Scholar 

Download references

Author information



Rights and permissions

Reprints and Permissions

About this article

Cite this article

CHARNOCK, J., LOCKETT, R. & HETZEL, B. Effect of Salicylate on Plasma Magnesium-Levels. Nature 195, 295–296 (1962).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing