Abstract
PREVIOUS work has shown that small mechanical injuries to the epithelium of the rabbit lens can initiate a wave of stimulation to synthesis of DNA and mitosis. The number of cells stimulated to divide is relatively large compared with the size of the injury itself. This reaction is being examined in order to gain a better understanding of the relationship between injury and the induction of cell division.
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References
Harding, C. V., Feldherr, C., and Srinivasan, B. D., in The Structure of the Eye, edit. by Smelser, G., 273 (Academic Press, Inc., New York, 1961).
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Harding, C. V., Hughes, W. L., Bond, V. P., and Schork, P., Amer. Med. Assoc. Arch. Ophth., 63, 58 (1960).
Harding, C. V., Donn, A., and Srinivasan, B. D., Exp. Cell. Res., 18, 582 (1959).
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ROTHSTEIN, H., HARDING, C. Injury-induced Synthesis of Deoxyribonucleic Acid in the Lens of the Sea Bass. Nature 194, 294–295 (1962). https://doi.org/10.1038/194294a0
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DOI: https://doi.org/10.1038/194294a0
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