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Effect of ‘Busulphan’ (‘Myleran’) on the Spermatogenic Cell Population of the Rat Testis

Nature volume 194, pages 1184–1185 (1962)Cite this article

Abstract

THE ability of alkylating agents to produce selective effects on spermatogenesis and sperm in rodents has been reported in several publications1–3. A comparison of the timing of sterile periods after treatment with the accepted duration of spermatogenic events in the testis has enabled the phase of spermatogenesis affected by particular compounds to be located.

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References

  1. Bock, M., and Jackson, H., Brit. J. Pharmacol., 12, 1 (1957).

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  2. Jackson, H., Craig, A. W., and Fox, B. W., Brit. J. Pharmacol., 14, 149 (1959).

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  3. Jackson, H., Fox, B. W., and Craig, A. W., J. Reprod. and Fertil., 2, 447 (1961).

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  4. Leblond, C. P., and Clermont, Y., Amer. J. Anat., 90, 167 (1952).

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  5. Clermont, Y., Leblond, C. P., and Messier, B., Arch. D'Anatomie Microscopique et de Morphologie Experimentale, 48, 37 (1959).

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Authors and Affiliations

  1. Department of Experimental Chemotherapy, Christie Hospital, Manchester, 20

    H. JACKSON, MARGARET PARTINGTON & B. W. FOX

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  1. H. JACKSON
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  2. MARGARET PARTINGTON
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  3. B. W. FOX
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JACKSON, H., PARTINGTON, M. & FOX, B. Effect of ‘Busulphan’ (‘Myleran’) on the Spermatogenic Cell Population of the Rat Testis. Nature 194, 1184–1185 (1962). https://doi.org/10.1038/1941184b0

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