A PREVIOUS communication1 has described a repeatable technique for the fertilization in vitro of rabbit ova, the transfer of which to recipient females resulted in the subsequent delivery of viable young. However, in these and experiments of other workers2,3 the rate of fertilization so far achieved in vitro is much below the 94 per cent4,5 normally obtained in vivo. Thus, it would seem to be of interest to report on the results of experiments carried out in an effort to raise the percentage of fertilization in vitro, and on some factors which may affect mammalian fertilization.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Chang, M. C., Nature, 184, 466 (1959).
Dauzier, L., Thibault, C., and Wintenburger, S., C.R. Acad. Sci., Paris, 238, 844 (1954).
Dauzier, L., and Thibault, C., C.R. Acad. Sci., Paris, 248, 2655 (1959).
Chang, M. C., Fert. and Ster., 3, 251 (1952).
Adams, C. E., J. Endocrinol., 13, 296 (1956).
Hammond, jun., J., Nature, 163, 28 (1949).
Dauzier, L., and Thibault, C., Fourth Intern. Cong. Anim. Rep. and Art. Ins., The Hague (1961).
Chang, M. C., Nature, 179, 258 (1957).
Thibault, C., and Dauzier, L., C.R. Acad. Sci., Paris, 250, 1358 (1960).
Runnstrom, J., Exp. Cell Res., 12, 374 (1957).
About this article
Cite this article
BEDFORD, J., CHANG, M. Fertilization of Rabbit Ova in vitro. Nature 193, 898–899 (1962). https://doi.org/10.1038/193898a0