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Dissociation of Thrombosthenin into Two Components comparable with Actin and Myosin

Nature volume 193, pages 777–778 (1962)Cite this article

Abstract

BLOOD platelets are capable of inducing the retraction of blood clots as well as of undergoing morphological and structural changes termed ‘viscous metamorphosis’. Both phenomena are manifestations of the same basic processes, and they are interlinked with the important functions of platelets in the hæmostatic mechanism. In 1959 we reported the isolation of a contractile protein from human blood platelets1. This material, afterwards termed ‘thrombosthenin’, accounts for 15 per cent of the platelet proteins, and most likely plays an important part in the functions of the platelet2.

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References

  1. Bettex-Galland, M., and Lüscher, E. F., Nature, 184, 276 (1959).

    Article  ADS  CAS  Google Scholar 

  2. Bettex-Galland, M., and Lüscher, E. F., Biochim. Biophys. Acta, 49, 536 (1961).

    Article  CAS  Google Scholar 

  3. Hoffmann-Berling, H., Biochim. Biophys. Acta, 19, 453 (1956).

    Article  CAS  Google Scholar 

  4. Szent-Györgyi, A. G., J. Biol. Chem., 192, 361 (1951).

    PubMed  Google Scholar 

  5. Bárány, M., Bárány, K., and Guba, F., Nature, 179, 818 (1957).

    Article  ADS  Google Scholar 

  6. Bárány, M., and Jaisle, F., Biochim. Biophys. Acta, 41, 192 (1960).

    Article  Google Scholar 

  7. Portzehl, H., Schramm, G., and Weber, H. H., Z. Naturforsch., 5, b, 61 (1950).

    Article  Google Scholar 

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Authors and Affiliations

  1. Theodor Kocher Institute, University of Berne,

    M. BETTEX-GALLAND, H. PORTZEHL & E. F. LÜSCHER

Authors
  1. M. BETTEX-GALLAND
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  2. H. PORTZEHL
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  3. E. F. LÜSCHER
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BETTEX-GALLAND, M., PORTZEHL, H. & LÜSCHER, E. Dissociation of Thrombosthenin into Two Components comparable with Actin and Myosin. Nature 193, 777–778 (1962). https://doi.org/10.1038/193777a0

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