Letter | Published:

Dissociation of Thrombosthenin into Two Components comparable with Actin and Myosin

Nature volume 193, pages 777778 (24 February 1962) | Download Citation

Subjects

Abstract

BLOOD platelets are capable of inducing the retraction of blood clots as well as of undergoing morphological and structural changes termed ‘viscous metamorphosis’. Both phenomena are manifestations of the same basic processes, and they are interlinked with the important functions of platelets in the hæmostatic mechanism. In 1959 we reported the isolation of a contractile protein from human blood platelets1. This material, afterwards termed ‘thrombosthenin’, accounts for 15 per cent of the platelet proteins, and most likely plays an important part in the functions of the platelet2.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , and , Nature, 184, 276 (1959).

  2. 2.

    , and , Biochim. Biophys. Acta, 49, 536 (1961).

  3. 3.

    , Biochim. Biophys. Acta, 19, 453 (1956).

  4. 4.

    , J. Biol. Chem., 192, 361 (1951).

  5. 5.

    , , and , Nature, 179, 818 (1957).

  6. 6.

    , and , Biochim. Biophys. Acta, 41, 192 (1960).

  7. 7.

    , , and , Z. Naturforsch., 5, b, 61 (1950).

Download references

Author information

Affiliations

  1. Theodor Kocher Institute, University of Berne.

    • M. BETTEX-GALLAND
    • , H. PORTZEHL
    •  & E. F. LÜSCHER

Authors

  1. Search for M. BETTEX-GALLAND in:

  2. Search for H. PORTZEHL in:

  3. Search for E. F. LÜSCHER in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/193777a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.