Abstract
IN connexion with work on tetrahydroquinoline derivatives of medicinal interest, we have recently synthesized a number of alkoxy- and alkyl-substituted 1,2,3,4-tetrahydroquinolines1 in which various dialkylaminoalkyl groups (carrying in some cases heterocyclic residues such as morpholino, piperidino, etc.) are linked directly to the nitrogen atom. Among the compounds tested so far, N-[2-(4-morpholino) ethyl]1,2,3,4-tetrahydroquinoline (I) has shown interesting biological activity.
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References
Thyagarajan, G., Sidhu, G. S., and Zaheer, S. H., Indian Patents 70175 and 76681.
Kacker, I. K., and Zaheer, S. H., J. Ind. Chem. Soc., 28, 344 (1951).
Gillis, C. N., and Lewis, J. J., J. Pharm. Pharmacol., 8, 606 (1956).
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SIDHU, G., THYAGARAJAN, G. & ZAHEER, S. New Potent Tetrahydroquinoline Derivative. Nature 193, 692 (1962). https://doi.org/10.1038/193692a0
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DOI: https://doi.org/10.1038/193692a0
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