Letter | Published:

New Potent Tetrahydroquinoline Derivative

Naturevolume 193page692 (1962) | Download Citation

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Abstract

IN connexion with work on tetrahydroquinoline derivatives of medicinal interest, we have recently synthesized a number of alkoxy- and alkyl-substituted 1,2,3,4-tetrahydroquinolines1 in which various dialkylaminoalkyl groups (carrying in some cases heterocyclic residues such as morpholino, piperidino, etc.) are linked directly to the nitrogen atom. Among the compounds tested so far, N-[2-(4-morpholino) ethyl]1,2,3,4-tetrahydroquinoline (I) has shown interesting biological activity.

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References

  1. 1

    Thyagarajan, G., Sidhu, G. S., and Zaheer, S. H., Indian Patents 70175 and 76681.

  2. 2

    Kacker, I. K., and Zaheer, S. H., J. Ind. Chem. Soc., 28, 344 (1951).

  3. 3

    Gillis, C. N., and Lewis, J. J., J. Pharm. Pharmacol., 8, 606 (1956).

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Affiliations

  1. Regional Research Laboratory, Hyderabad, 9

    • G. S. SIDHU
    • , G. THYAGARAJAN
    •  & S. H. ZAHEER

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https://doi.org/10.1038/193692a0

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