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Functional Uptake of Hydrazine by Frog Nerve in Sodium-deficient Ringer's Solution

Naturevolume 193pages691692 (1962) | Download Citation



LORENTE DE Nó et al.1 found that among the onium ions tested, the hydrazinium ion (HZ+) could maintain, for a long time, the compound action potential of the frog sciatic nerve in a sodium-free Ringer's solution. (Ringer's solution, identical to Ringer's solution B in ref. 6; HZ- or choline-Ringer's solution, similar to above except sodium was replaced by HZ or choline respectively.) In line with the general interest in this laboratory in the metabolism of nitrogenous compounds in nervous tissue, the relation between the HZ+ and the functional activity of nerve was further explored.

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  1. New York State Psychiatric Institute, 722 West 118th Street, New York



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