Letter | Published:

Rapid Method for Determination of Decarboxylation of Compounds labelled with Carbon-14

Naturevolume 193pages684685 (1962) | Download Citation



A RAPID and accurate method of determining the rate of decarboxylation activity of tissues in different types is presented. This method is based on the evolution of 14CO2 from substrate on filter papers impregnated with potassium hydroxide. Filter papers having radioactive compounds has been measured directly by liquid scintillation counting1–3.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Wang, C. H., and Jones, D. E., Biochem. Biophys. Res. Comm., 1, 203 (1959).

  2. 2

    Loftfteld, R. B., and Eigner, E. A., Biochem. Biophys. Res. Comm., 3, 72 (1960).

  3. 3

    Funt, B. L., and Hetherington, C., Science, 131, 1608 (1960).

  4. 4

    Operational Manual. Packard Tri-Carb Liquid Scintillation Spectrometer (Packard Instrument Co., Inc.).

  5. 5

    Burns, J. J., Julian, K., and Dayton, P. G., J. Biol. Chem., 232, 107 (1958).

Download references

Author information


  1. University of Tennessee–Atomic Energy Commission, Agricultural Research Laboratory, Oak Ridge, Tennessee

    •  & D. N. ROY


  1. Search for J. CHIRIBOGA in:

  2. Search for D. N. ROY in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.