Letter | Published:

Liberation of Acetylcholine from the Small Intestines of Guinea Pigs and Cats after Treatment with Picric Acid

Naturevolume 193pages589590 (1962) | Download Citation



DURING work on drug antagonism, it was found incidentally that isolated small intestines of guinea pigs contracted reversibly with picric acid, and the mode of this action was examined in detail, using the organ bath of 30 ml. at the bath temperature of 26° C., on isolated small intestines of guinea pigs1. All the results given here are the mean of at least ten experiments.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Takagi, K., and Kimura, M., Pharm. Bull., 5, 440 (1957). Takagi, K., and Takayanagi, I., ibid., 5, 580 (1957).

  2. 2

    Takayanagi, I., Chem. Pharm. Bull., 9, 187 (1961).

  3. 3

    Schaumann, W., Brit. J. Pharmacol., 10, 456 (1955).

Download references

Author information


  1. Department of Chemical Pharmacology, University of Tokyo, Bunkyo-ku, Tokyo

    • K. TAKAGI
    •  & I. TAKAYANAGI


  1. Search for K. TAKAGI in:

  2. Search for I. TAKAYANAGI in:

About this article

Publication history

Issue Date




By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.