Letter | Published:

Effect of Particle Size on Blood Griseofulvin-Levels in Man

Nature volume 193, pages 588589 (10 February 1962) | Download Citation

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Abstract

FOR some drugs both the degree of alimentary absorption and the consequent levels in the blood are inversely related to particle size. Here we summarize the results of experiments to investigate the relationship between the particle-size of griseofulvin and its level in the blood after oral administration of the drug.

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References

  1. 1.

    , and , Indust. Eng. Chem. (Anal. Ed.), 12, 479 (1940).

  2. 2.

    , , and , Nature, 184, 364 (1959).

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Affiliations

  1. Glaxo Laboratories, Greenford Road, Greenford, Middlesex.

    • R. M. ATKINSON
    • , CAROLE BEDFORD
    • , K. J. CHILD
    •  & E. G. TOMICH

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DOI

https://doi.org/10.1038/193588a0

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